Clinical trial tag: Platinum-sensitive

 

GLORIOSA: A study of Mirvetuximab Soravtansine and Bevacizumab as Maintenance therapy in Platinum-sensitive Ovarian Cancer

The trial is currently recruiting patients who have experienced a recurrence of ovarian, fallopian, or primary peritoneal cancer six months or more after receiving platinum-based chemotherapy. Maintenance treatments (also known as targeted treatments)work on specific genes and proteins that are involved in the growth and survival of cancer cells. T…

Woman with ovarian cancer in a treatment room looking down as a nurse provides chemotherapy

ACTOv: A trial of adaptive chemotherapy in relapsed platinum-sensitive ovarian cancer

Researchers in this trial are looking to find out whether a new way of giving carboplatin chemotherapy (adaptive therapy "AT") is as safe as and more effective than the current standard way of giving carboplatin in women with advanced recurrent ovarian cancer.Recurrent ovarian cancer is usually treated with chemotherapy. The chemotherapy aims to ki…

Closed trial

MOLTO: A trial looking at second course olaparib in BRCA positive recurrent ovarian cancer

Olaparib is a type of targeted treatment known as a PARP inhibitor. It blocks an enzyme called PARP, which helps damaged cancer cells to repair themselves. When PARP doesn't work the cancer cells won't be able to repair themselves and will die. Because of this, drugs such as olaparib are known to lengthen the amount of time between receiving chemot…

Close up of two people with painted nails holding hands
Closed trial

ICON9: A study of olaparib and cediranib in recurrent ovarian cancer

This trial looks to answer the question as to whether two different types of anti-cancer drugs, given as maintenance treatment are: safe effective well-tolerated Maintenance treatment is a type of targeted therapy that is given to try to prevent or delay the cancer's return after it has responded to chemotherapy. …