Clinical trial tag: Cediranib

 

Closed trial

OCTOVA: A trial of olaparib and cediranib in recurrent ovarian cancer

This trial is looking to find better treatments for women with ovarian cancer that has come back. The trial is looking to find out if the drugs olaparib and cediranib are safe and work better than the standard chemotherapy drug paclitaxel. The drugs involved in this trial are: Paclitaxel – the known drug. This is a chemotherapy drug given …

Closed trial

MOLTO: A trial looking at second course olaparib in BRCA positive recurrent ovarian cancer

Olaparib is a type of targeted treatment known as a PARP inhibitor. It blocks an enzyme called PARP, which helps damaged cancer cells to repair themselves. When PARP doesn't work the cancer cells won't be able to repair themselves and will die. Because of this, drugs such as olaparib are known to lengthen the amount of time between receiving chemot…

Close up of a woman looking at Target Ovarian Cancer's website on her phone during chemotherapy
Closed trial

CEBOC: A study into the safety of cediranib in the prevention of bowel perforation

The main purpose of conducting the trial is to: determine the safety of combining cediranib, a VEGF inhibitor, with paclitaxel a weekly chemotherapy regime find out how well the treatment works in terms of shrinking the cancer and preventing bowel obstruction. If the cancer responds to this treatment then after the course of paclitaxel…

Close up of two people with painted nails holding hands
Closed trial

ICON9: A study of olaparib and cediranib in recurrent ovarian cancer

This trial looks to answer the question as to whether two different types of anti-cancer drugs, given as maintenance treatment are: safe effective well-tolerated Maintenance treatment is a type of targeted therapy that is given to try to prevent or delay the cancer's return after it has responded to chemotherapy. …